As a longevity scientist, Matt often receives questions about what supplements he takes—so we decided to make an episode where Matt discusses his supplements protocol.

This episode isn't meant to provide a playbook for you to follow. We want to emphasize the importance of approaching supplements with discernment and an understanding that they are not a substitute for wholesome nutrition and other healthy lifestyle practices. The allure of supplements is understandable: they promise us vitality, strength, and longevity in a convenient capsule. But their indiscriminate consumption can be risky. Blindly reaching for supplements without considering their necessity or potential interactions with medications could lead to adverse effects. Further, the supplement industry isn't rigorously regulated in many regions, leaving room for mislabeling and contamination. There is no such thing as a one-size-fits-all solution when it comes to supplements.

In this episode, Matt discusses his relatively conservative supplements approach, debunks some of the myths associated with supplement consumption, and provides some advice about how to evaluate products that come from a profit-driven industry with few guardrails in place.

Check out the links below for further information and/or reading about some of the things we discussed in this podcast episode. Note that we do not necessarily endorse or agree with the content of these readings, but present them as supplementary material that may deepen your understanding of the topic after you listen to our podcast. This list is in no way exhaustive, but it’s a good start!

Examine.com

Examine is an independently-funded (no gifts, donors, sponsors, consulting clients, advertisements, or affiliations) database of supplements research that provides information about benefits, dietary sources, dosage, side effects, and more for pretty much any supplement you can think of. The website provides further references from the primary literature about each supplement it discusses.

NAD and NAD precursors: help or hype? | Peter Attia, M.D. & Matt Kaeberlein, Ph.D.

Matt spoke with physician Peter Attia on the Peter Attia Drive podcast about the nuances of how nicotinamide adenine dinucleotide (NAD) precursors affect aging. He also discusses his views on the evidence for sirtuins' effects on lifespan.

Why EVERYONE Should Use Creatine Supplements

This episode of physician Brad Stanfield's Look & Feel Young podcast provides a quick primer on the benefits of creatine supplements, which include athletic performance and short-term memory improvements, among others. It also addresses concerns that people often have with creatine supplementation, such as hair loss.