News
Latest News & Appearances
Research notes from our clinicians, Optispan in the press, and every issue of our newsletter.
In the News|
Dr. Nicki Byrne with the Puget Sound Business Journal
Optispan Medical Director Dr. Nicki Byrne took the stage at the Puget Sound Business Journal's Washington's Best Workplaces celebration, an evening recognizing the…
Insights|
Two Sheet Pan Salmon Dinners from Dr. Nicki Byrne
I get asked what I actually cook at home more often than I get asked about almost anything else in clinic. Not what I recommend, but what I make, on a Wednesday, when…
Insights|
The FDA Did Not Approve Peptides. Here Is What Actually Happened.
Your feed might have told you that the FDA approved peptides. That is not exactly what happened, and the gap between the headline and the actual decision matters if…
Insights|
Two Protein-Forward Chicken Dinners from Dr. Nicki Byrne
Most people don't fall short on healthy eating because they lack information. They fall short because the meal in front of them at 6:45pm on a Tuesday isn't the meal…
In the News|
Life Science Daily News: The Evidence Gap in Precision Prevention
Preventive medicine is entering a new era. Advances in genomics, biomarker testing, continuous monitoring technologies, imaging, and data analytics are enabling…
Insights|
Your Sleep and Your Hormones are in a Loop
Most sleep advice treats hormones as a one-way street: balance your hormones, and better sleep will follow. It is a reasonable assumption, and it is not wrong. But it…
In the News|
KIRO 7 News Seattle: Federal officials want to speed up clinical trials - by using A.I
Well, the Federal Drug Administration now wants to shake up clinical trials using AI. The goal here is potentially cut years off the timeline to develop new drugs much…
Insights|
Power Is the First Thing You Lose. Your Broad Jump Measures It.
A two-second test that reads a system your bloodwork can't see, and what your number actually means. If you watched the short, you already know the question: can you…
Insights|
The Fastest Way to Bond With a Stranger Isn't Conversation. It's Awe.
Awe is the feeling that washes over you when the world turns out to be bigger than you imagined, standing under a night sky, hearing music that seems to stop time…
Insights|
Social Relationships and Longevity: How They Connect
We know that social relationships impact healthspan. But I had no idea how much. A new study just identified what separates "superagers", people in their 80s who score…
In the News|
CityBiz: Q&A with Dr. Nicole Byrne, Clinical Director at Optispan
Dr. Nicole Byrne is the Clinical Director at Optispan, Inc, the Seattle-based longevity and precision medicine company focused on evidence-based healthspan…
Newsletter|
The Big O | April 2026 Newsletter
Power Up Your Cells: Mitochondria and Longevity At Optispan, we don’t think small; we aim for exponential impact. The Big O notation* represents the growth of…
Newsletter|
The Big O | March 2026 Newsletter
Sharper Minds, Longer Lives At Optispan, we don’t think small; we aim for exponential impact. The Big O notation* represents the growth of complexity in algorithms. At…
In the News|
Business Insider: A longevity researcher started taking testosterone in his 50s. He says there are 4 things everyone should know before considering TRT
In 2020, longevity researcher and OptiSpan CEO Matt Kaeberlein began noticing the classic signs of low testosterone, declining energy, a significant drop in libido…
Newsletter|
The Big O | February 2026 Newsletter
Bone Density & Joint Health At Optispan, we don’t think small; we aim for exponential impact. The Big O notation* represents the growth of complexity in algorithms. At…
In the News|
Past, Present and Future Perspectives on the Science of Aging
As Nature Aging celebrates its fifth anniversary, the journal asks some of the researchers who contributed to the journal early on to reflect on the past and the…
In the News|
Geroscience in 2025: The Expert Roundup
2025 was a good year for geroscience, marked by rapid strides and critical milestones. Yet, the path wasn’t always smooth: progress in some areas lagged, research hit…
Insights|
Building (and Maintaining) Bone Density: The Lifestyle Foundation for Resilient Aging
If bone is foundational infrastructure—and the data makes clear that it is—then our Eat, Move, Sleep, and Connect Pillars becomes the daily maintenance protocol that…
In the News|
Business Insider profile: Matt Kaeberlein’s 4 habits for healthier aging
On a February 7, 2026 Business Insider feature, Optispan CEO and longevity researcher Matt Kaeberlein describes how he reshaped his lifestyle after moving from…
In the News|
Matt Kaeberlein’s Daily Longevity Routine: Featured in CNBC
In a recent CNBC Make It interview, Optispan CEO and longtime longevity researcher Matt Kaeberlein shares the daily habits he’s built to improve healthspan—especially…
Newsletter|
The Big O | January 2026 Newsletter
This edition of Optispan News frames the company’s mission through “The Big O” lens: scaling impact the way great systems scale—efficiently and exponentially. Matt…
Newsletter|
The Big O | December 2025 Newsletter
As 2025 draws to a close, Optispan has reached significant milestones. Our team has strengthened and aligned around our mission, and under Dr. Byrne's leadership, our…
In the News|
Forbes | The Best Biomarkers For Longevity, According To Experts
Modern medicine has been remarkably successful at extending lifespan, but further gains are likely to come from improving healthspan—the years lived in good physical…
Newsletter|
The Big O | November 2025 Newsletter
Dr. Kaeberlein shared two straightforward diet changes with Fit & Well : cut back on ultra-processed foods (calorie-dense, nutrient-poor, and promote inflammation) and…
In the News|
Fit & Well | A longevity expert says these are the two changes to make to your diet if you want to live a long, healthy life
Newsletter|
The Big O | October Newsletter
Dr Nicki Byrne breaks down Heart Rate Variability (HRV), and how it has emerged as one of the most practical tools for assessing how patients are truly doing, not just…
In the News|
Medium's Authority Magazine | Discovering Your Life’s Purpose: Dr Matt Kaeberlein of Optispan On How to Align Your Goals with Your True Self.
Our CEO, Dr. Matt Kaeberlein, was recently featured in an article published in Medium’s Authority Magazine. The article covers how Matt has built his work around…
In the News|
Why Healthspan Medicine Matters | Psychology Today
On September 24th, Our CEO Dr. Matt Kaeberlein authored an article published by Psychology today, discussing why healthspan medicine matters and how combining mental…
Newsletter|
The Big O | September 2025
September Highlights We’re excited to introduce three new colleagues who have recently joined Optispan. Please join us in giving them a warm welcome as they get…
In the News|
Real Simple | 4 Simple Challenges That Reveal How Well Your Body Is Really Aging
In a recent article published by Real Simple , our CEO Dr. Matt Kaeberlein was consulted regarding what happens to our body as we age. This complimented the dialogue…
Insights|
A Deep Dive into the Optispan Team's Training for VO₂ Max
Learn more about the Optispan Team’s Training for VO₂ Max.
In the News|
Lifespan.io: Two People Almost Died At RAADFest
The longevity field is fueled by strong public desire for healthier, longer lives—but approved anti-aging treatments remain elusive, often prompting individuals to…
In the News|
Thousands of dogs are already trying the first life-extending pill: "They could gain the equivalent of 24 human years."
The Spanish newspaper elDiario.es recently reported on two groundbreaking clinical trials in the United States that are testing the world’s first longevity pills in…
Newsletter|
The Big O | August 2025 Newsletter
At Optispan, we don’t think small, we aim for exponential impact. The Big O notation* represents the growth of complexity in algorithms. At Optispan, we take a similar…
Press Release|
Dr. Kaeberlein Speaks at CTGN’s 2nd Scientific Meeting
Our CEO, Dr. Matt Kaeberlein, will be speaking at the Canadian Translational Geroscience Network’s 2nd Scientific Meeting of the Canadian Translational Geroscience…
In the News|
Business Insights Journal Interview with Dr. Matt Kaeberlein CEO of Optispan
In a recent interview conducted by Business Insider, Our CEO, Dr Matt Kaeberlein, shared how Optispan is redefining longevity care through science-driven, personalized…
In the News|
Q&A with Dr. Matt Kaeberlein, World-Renowned Longevity Expert and CEO of Optispan.
Dr. Matt Kaeberlein is the Chief Executive Officer at Optispan and host of the Optispan Podcast . He is also an Affiliate Professor of Oral Health Sciences at the…
Newsletter|
The Big O | June 2025 Newsletter
Missed the June 2025 issue of the Big O newsletter? Get caught up here!
Newsletter|
The Big O | March 2025 Newsletter
Missed the March 2025 issue of the Big O newsletter? Get caught up here!
In the News|
Scientific American | A Practical Approach to Healthspan Medicine
The U.S. healthcare system has long focused on reacting to illness rather than preventing it. But a growing movement—known as healthspan medicine —is challenging that…
Video|
Longevity Biologist Reveals Shocking Truth About Fasting, Autophagy & Longevity [Thomas DeLauer]
Fasting is often touted as a powerful tool for health and longevity, but the science behind it is far more complex than most headlines suggest. In this in-depth…
In the News · Video|
Fasting, Supplements & Tools for Aging Well [High Intensity Health]
Matt Kaeberlein, PhD dives into how rapamycin and tackling senescent cells could redefine aging, while spotlighting the crucial role of diet, exercise, and sleep.
In the News · Video|
Anti Aging with Nutrition [Inka Land]
Today, my guest is Dr. Matt Kaeberlein, a CEO of Optispan, anti-aging researcher, Professor at the University of Washington, and founding Director of the University of…
In the News|
Optimizing healthspan, empowering longevity clinics and exploring biological age. [Longevity.Technology]
Longevity.Technology wrote about Optispan’s mission to extend healthspan by shifting healthcare from reactive disease treatment, and its development of science-based…
In the News|
The new fluoride? FDA greenlights rapamycin oral health trial [Longevity.Technology]
Longevity.Technology wrote about Optispan’s collaboration with the RAPID trial to assess the efficacy of rapamycin in treating periodontal disease.
Press Release|
Optispan CEO Matt Kaeberlein Named "Healthcare Innovator of the Year" by Puget Sound Business Journal
For Immediate Release Seattle, WA – 12/7/23 – Optispan, a leading healthcare technology company, proudly announces that the the Puget Sound Business Journal has named…
Press Release|
Optispan Collaborates in Groundbreaking RAPID Clinical Trial to Tackle Periodontal Disease and Aging
For Immediate Release Seattle, WA – 12/4/23 – Optispan, a leading healthcare technology company based in Seattle, is proud to announce its collaboration in the…
In the News|
Biotech Teams are Gearing Up for a $101M Competition to Boost Healthy Lifespan [GeekWire]
GeekWire wrote that some of the biggest names in longevity research — including Optispan — will enter a $101 million, seven-year competition to turn back the clock on…
In the News · Video|
The Million Molecule Challenge for Life Extension [Longevity Summit Dublin]
The potency of therapeutics able to extend maximum healthy lifespan in mammals has stagnated, despite the explosive growth of the longevity sector: no new solution has…
In the News · Video|
Is Aging Solvable? [Khosla Ventures]
In the News · Video|
What & When To Eat To Slow the Aging Process [Impact Theory]
You just want to look better, feel better, have bigger muscles, tighter skin, and a sexier body you can enjoy and be proud of. The information and narratives floating…
In the News · Video|
The Science of Aging and How to Slow It Down [The Proof]
Humans have long been interested in the phenomenon of aging – today, scientists across the world are pursuing ways we can increase our lifespan. From pharmaceutical…
In the News|
What Science Tells Us About Living Longer [National Geographic]
Scientists are hard at work trying to understand what causes aging and how to help people stay healthy for longer. Biologist Matt Kaeberlein breaks down the science of…
In the News · Video|
The Dark Matter of Bioaging [ARDD]
The Aging and Drug Discovery Conference (ARDD) 2022 is pleased to present Matt Kabeirlein from The University of Washington, with the talk The dark matter of bioaging.…
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